Like many, I was getting an error when I updated my iTunes to version 7.3
"The iTunes Library file cannot be saved. An unknown error occurred (-50). "
I applied the fix I found on this site and it seems to have worked.
http://forums.macrumors.com/showthread.php?referrerid=59552&t=321921
I didn't have a ton of video podcasts but I deleted them and the error seems to have resolved itself.
Odd that Apple hasn't responded to this error yet though. Bad form...
